Cannabis vs. Hemp Oil: What Is The Difference?

Major Differences Between Cannabis and Hemp Oil

• Hemp oil comes from hemp seeds, while cannabis oil is made from the flowers and leaves.

• Hemp oil has less than 0.3% THC, while cannabis oil usually contains more than 0.3% THC.

• Hemp oil is non-psychoactive, while cannabis oil can produce a high.

• Hemp oil is used for nutrition, skincare, and inflammation, while cannabis oil is used for strong medical relief.

• Hemp oil is legal nationwide under the Farm Bill, while cannabis oil is restricted and requires a medical marijuana card in many states.

• Hemp oil is common in dietary supplements and beauty products, while cannabis oil is taken for therapeutic or recreational use.

• Hemp oil should be refrigerated to extend shelf life, while cannabis oil should be kept in a cool, dark place.

Introduction

As cannabis legalization spreads and wellness products flood the marketplace, many patients are left asking: What’s the difference between hemp oil and cannabis oil?

The two products are often confused, with some people even using them interchangeably. But this mistake can lead to misunderstandings about legality, potency, and health benefits. If you’re considering either hemp oil or cannabis oil for therapeutic use, it’s important to understand their origins, compositions, and unique effects.

This guide breaks down hemp oil vs. cannabis oil in detail, covering benefits, risks, legal status, and how to make informed decisions about your care.

Let’s dive in!

You May Also Read: CBD Tincture Vs Oil: Which is Better?

Origin and Composition: Hemp Oil vs. Cannabis Oil

Although hemp oil and cannabis oil both originate from the Cannabis sativa plant family, their source material, chemical makeup, and intended uses differ dramatically. Understanding these distinctions is crucial for patients and consumers who want to choose the right product for their health needs or wellness routines.

Hemp Oil

Hemp oil, sometimes called hemp seed oil, is produced by cold-pressing the seeds of the hemp plant, a non-intoxicating variety of Cannabis sativa. Because the seeds contain little to no cannabinoids, hemp oil is naturally very low in THC (tetrahydrocannabinol), the psychoactive compound responsible for producing a “high.” By law in the United States, hemp is defined as cannabis that contains no more than 0.3% THC on a dry weight basis, ensuring that hemp oil remains non-psychoactive and widely legal.

While the seed itself does not contain significant CBD (cannabidiol), hemp oil can still be rich in beneficial plant compounds such as omega fatty acids, proteins, vitamins, and trace minerals. Its extraction process resembles that of other culinary oils, such as olive oil or sunflower oil, making it a versatile product that can be used for cooking, skincare, and general wellness.

Because of its nutritional composition and minimal THC content, hemp oil is not used for recreational purposes. Instead, it is often consumed as a dietary supplement to promote heart health, used topically for skincare and inflammation, or incorporated into foods like protein bars, baked goods, and smoothies.

Related: How To Germinate Marijuana Seeds?

Cannabis Oil

Cannabis oil, sometimes referred to as marijuana oil or THC oil, comes from the flowers, leaves, and sometimes the stems of cannabis plants that are bred for their high cannabinoid content. Unlike hemp oil, cannabis oil contains significant concentrations of THC, making it a psychoactive product. Depending on the strain used and the extraction process, cannabis oil may also contain high levels of CBD, terpenes, and other beneficial plant compounds.

Cannabis oil is extracted using specialized techniques such as solvent extraction, CO₂ extraction, or ethanol-based methods. These processes allow manufacturers to capture not only THC and CBD but also a range of terpenes and flavonoids that contribute to the oil’s therapeutic potential and unique aroma. Because of its THC content, cannabis oil produces intoxicating effects and is strictly regulated by law, often requiring patients to obtain a medical marijuana card for legal access.

Unlike hemp oil, cannabis oil is not primarily a nutritional product, it is a therapeutic preparation used to relieve symptoms of chronic pain, anxiety, PTSD, nausea, and other conditions. The specific composition of cannabis oil depends on the strain and processing method, but its hallmark distinction is its psychoactive potency and medical-grade efficacy.

Potency and Efficacy: CBD vs. THC

One of the most important distinctions between hemp oil and cannabis oil lies in their potency and how they interact with the human body. This difference comes down to their dominant cannabinoids, CBD (cannabidiol) and THC (tetrahydrocannabinol), which produce very different therapeutic and physiological effects.

Hemp Oil (CBD-Rich, Low THC)

Hemp oil is non-psychoactive because it contains little to no THC. Its appeal comes from its higher concentration of CBD, a cannabinoid that interacts with the body’s endocannabinoid system (ECS). The ECS regulates essential functions such as mood, sleep, pain perception, memory, and immune response.

CBD has been widely studied for its potential therapeutic benefits, including:

• Chronic pain relief without the risk of intoxication.

• Anti-inflammatory properties, helpful for conditions like arthritis or inflammatory bowel issues.

• Anxiety and stress reduction, providing calming effects without impairment.

• Neuroprotective potential, with studies suggesting possible benefits for epilepsy, Alzheimer’s disease, and multiple sclerosis.

• Cancer-related symptom relief, such as reducing nausea, vomiting, and discomfort from treatments like chemotherapy.

Because hemp oil is lower in THC, patients often consider it safer for daily use, particularly for individuals who wish to avoid the “high” or psychoactive effects of cannabis.

Cannabis Oil (THC-Rich, Variable CBD)

Cannabis oil, by contrast, contains significantly higher levels of THC. THC is the primary psychoactive compound in cannabis and binds strongly to the CB1 receptors in the brain, creating feelings of euphoria, relaxation, and altered perception. For some patients, this intoxicating effect is therapeutic, while for others it may be undesirable.

Medical benefits associated with THC-rich cannabis oil include:

• Potent pain relief, particularly for neuropathic pain that does not respond well to traditional medications.

• Appetite stimulation, often helpful for patients with cancer, HIV/AIDS, or eating disorders.

• Relief from severe nausea and vomiting, especially chemotherapy-induced nausea.

• Muscle relaxation and spasm reduction, often used by patients with multiple sclerosis.

• Improved sleep, as THC may reduce the time it takes to fall asleep.

However, THC also carries risks and side effects such as impaired memory, reduced coordination, anxiety, or dependency if not used under medical supervision.

The Entourage Effect

A growing body of anecdotal evidence and emerging research supports the concept of the entourage effect. This theory suggests that cannabinoids like CBD and THC, when combined with terpenes and flavonoids, may provide greater therapeutic benefits than when taken in isolation.

For example:

• CBD may reduce some of the anxiety-inducing effects of THC, making the experience more tolerable.

• THC may enhance the pain-relieving potential of CBD, especially for patients with severe chronic conditions.

• Terpenes (such as myrcene, limonene, and linalool) may contribute their own unique properties, from calming effects to anti-inflammatory activity.

That said, the entourage effect is still being studied, and while promising, it should not be viewed as universally applicable to every patient or condition.

Related: Does CBD Oil Go Bad?

Nutritional Benefits of Hemp Oil

Hemp oil is not only valued for its gentle therapeutic qualities but also for its exceptional nutritional profile, which makes it a sought-after dietary supplement and wellness product. Unlike cannabis oil, which is primarily used for its psychoactive and therapeutic compounds, hemp oil functions as a nutrient-rich superfood that can be incorporated into daily health routines.

1. Rich in Essential Fatty Acids

One of the standout features of hemp oil is its abundance of omega fatty acids, specifically omega-3 and omega-6. These fatty acids play a vital role in supporting cardiovascular health, brain function, and the regulation of cholesterol levels. Hemp oil provides them in an almost ideal 3:1 ratio, which is considered optimal for human health. This balance supports:

• Improved heart health by reducing bad cholesterol (LDL) levels.

• Enhanced brain function and focus through better nerve signaling.

• Reduced inflammation, which can help with conditions like arthritis and metabolic disorders.

2. Gamma-Linolenic Acid (GLA) for Anti-Inflammatory Support

Hemp oil also contains gamma-linolenic acid (GLA), a rare type of omega-6 fatty acid with strong anti-inflammatory properties. GLA has been linked to benefits for people dealing with conditions such as eczema, psoriasis, rheumatoid arthritis, and even PMS-related symptoms. For many patients, incorporating hemp oil into their diet can provide a natural alternative to anti-inflammatory medications.

3. Plant-Based Protein and Micronutrients

While not a complete replacement for whole hemp seeds, hemp oil still retains valuable plant-based proteins and amino acids, making it appealing to vegetarians, vegans, and anyone looking to diversify their protein intake. Additionally, hemp oil provides a range of vitamins and minerals, including:

• Vitamin E, a powerful antioxidant that supports skin health and protects against free radicals.

• Magnesium, which is critical for nerve function and muscle relaxation.

• Zinc, essential for immune system regulation and wound healing.

• Iron, necessary for healthy red blood cell production.

4. Digestive and Metabolic Benefits

Hemp oil has a light, nutty flavor and a smooth texture that makes it easy to add to foods. Because it is minimally processed and plant-based, it is also highly digestible. Regular consumption may support:

• Improved digestion through its natural oils that aid in nutrient absorption.

• Balanced metabolism by helping regulate blood sugar and fat storage.

• Energy production, as its fatty acids are a clean-burning fuel source for the body.

5. Culinary and Skincare Uses

The versatility of hemp oil extends beyond nutrition. In the kitchen, it can be drizzled over salads, blended into smoothies, or used in homemade salad dressings. Its nutty, earthy taste enhances a wide variety of dishes without overpowering them.

In addition to dietary use, hemp oil is widely integrated into skincare and beauty products. Thanks to its moisturizing properties and high vitamin E content, it helps:

• Alleviate dry skin and flakiness.

• Reduce redness and irritation caused by inflammation.

• Improve skin elasticity and appearance by keeping it hydrated and nourished.

6. A Wellness Oil for Everyday Life

Because it does not contain psychoactive THC, hemp oil can be used daily without concern for intoxication. Its combination of fatty acids, vitamins, antioxidants, and plant proteins makes it a multi-functional wellness supplement—supporting heart health, skin health, and overall vitality.

Cannabis Oil’s Therapeutic Profile

Cannabis oil isn’t typically used in diets, but it contains:

• Terpenes, which can have anti-inflammatory or calming effects.

• Flavonoids, plant compounds linked to antioxidant and neuroprotective benefits.

• Stronger medical applications, especially when high THC content is needed for symptom relief.

Accessibility and Legality

Hemp Oil

• Widely legal across the U.S. thanks to the 2018 Farm Bill, which legalized hemp products with <0.3% THC.

• Easily purchased at supermarkets, health food stores, pharmacies, and online.

• No prescription needed.

Cannabis Oil

• Legal status is state-specific.

• In Virginia, cannabis oil is only available to patients with a medical marijuana card.

• Often requires a prescription and purchase through licensed dispensaries.

• Still classified as illegal under federal law, though enforcement has relaxed in states with legalization.

Key takeaway: While hemp oil is accessible as an over-the-counter wellness product, cannabis oil is regulated and requires proper medical certification in many states.

Preservation and Shelf Life

Proper storage is key to maintaining quality.

Hemp Oil

• Store in a cool, dark place (ideally refrigerated).
  Watch for signs of spoilage such as a sour smell or cloudy appearance.

• Best used within 6–12 months.

Cannabis Oil

• Store in airtight containers away from heat, light, and moisture.
  Refrigeration can extend shelf life.
  Must be kept out of children’s reach due to psychoactive effects.

Also Read: Common Mistakes When Using CBD Oil

Safety and Medical Oversight

Both hemp oil and cannabis oil can provide therapeutic benefits, but patients should use caution:

• Hemp Oil Risks: Generally safe, though some claims remain unproven. May interact with medications such as blood thinners.

• Cannabis Oil Risks: Stronger effects, potential for dependency, and risk of impairment.

Why Medical Supervision Matters

Self-medicating can be dangerous. Patients with chronic conditions should consult a licensed medical marijuana doctor who can:

• Assess eligibility for a medical marijuana card.

• Recommend proper dosage and product types.

• Monitor for side effects or drug interactions.

Common Misconceptions

Because hemp oil and cannabis oil both come from the Cannabis sativa plant family, it’s easy to see why people confuse them. However, these misunderstandings can lead to improper use, legal trouble, or disappointment in results. 

Let’s break down the most frequent misconceptions and clarify the facts.

1. Hemp oil and cannabis oil are the same thing.

This is one of the most widespread myths. While both oils originate from the cannabis plant, their source parts and chemical composition differ greatly. Hemp oil comes from pressed hemp seeds and is mostly valued for its nutritional and skincare benefits. Cannabis oil, on the other hand, is extracted from flowers, leaves, and stems, making it rich in cannabinoids like THC and CBD. Treating them as the same can cause patients to use the wrong product for their needs.

2. Hemp oil can get you high.

Completely false. By legal definition, hemp oil contains less than 0.3% THC, which is far too low to cause any intoxicating effects. Hemp oil is considered safe for everyday use and is available without restrictions in most countries. If you’re looking for symptom relief without impairment, hemp oil is the right choice.

3. Cannabis oil is just another name for CBD oil.

This is another common misconception that leads to confusion at dispensaries and online shops. CBD oil is specifically formulated to contain high amounts of cannabidiol (CBD) with minimal THC. Cannabis oil, however, often contains significant levels of THC and produces psychoactive effects. While cannabis oil may contain CBD, if the THC content is above 0.3%, it is not considered CBD oil. Patients should always check product labels carefully.

4. Both oils are legal everywhere.

Not true. Hemp oil is widely legal thanks to the 2018 U.S. Farm Bill, which removed hemp from the list of controlled substances, provided THC content stays under 0.3%. Cannabis oil, however, remains regulated due to its high THC levels. In Virginia and many other states, you must have a medical marijuana card to legally obtain cannabis oil. Federally, cannabis is still illegal, which can create confusion when traveling or purchasing across state lines.

5. Hemp oil has no real health benefits.

Some people dismiss hemp oil as just a trendy wellness fad, but research shows it has genuine nutritional and therapeutic properties. Its rich blend of omega-3 and omega-6 fatty acids, gamma-linolenic acid, vitamin E, and plant proteins makes it beneficial for heart health, skin hydration, and inflammation reduction. While it doesn’t provide the same potent relief as cannabis oil, hemp oil is far from useless.

6. Cannabis oil is unsafe for medical use.

While cannabis oil does contain THC and produces psychoactive effects, labeling it as “unsafe” is misleading. Under medical supervision, cannabis oil can provide powerful relief for chronic pain, chemotherapy-induced nausea, PTSD, and other severe conditions. The key factor is responsible use and proper dosage guidance from a medical professional.

How to Decide Between Hemp Oil and Cannabis Oil

Choose hemp oil if:

• You want nutritional or skincare benefits.

• You need CBD but want to avoid intoxication.

• You live in a state where cannabis is not legal.

Choose cannabis oil if:

• You require stronger relief for conditions like cancer pain, PTSD, or severe anxiety.

• You have access to a medical marijuana card.

• You are comfortable with THC’s psychoactive effects.

Bottom Line

Hemp oil and cannabis oil may share a plant family, but their differences are significant.

• Hemp oil is nutrient-rich, non-intoxicating, and widely legal—ideal for those seeking mild relief or health supplements.

• Cannabis oil, with its higher THC content, offers stronger therapeutic potential but comes with legal restrictions and psychoactive effects.

For patients in Virginia, the safest and most reliable way to explore cannabis oil is through a certified provider.

Get Started With Medical Marijuana in Virginia

If you’re considering cannabis oil for therapeutic use, the first step is obtaining a Virginia medical marijuana card. At CannabisMD TeleMed, our team of board-certified doctors provides:

• Telemedicine consultations from the comfort of your home.

• Guidance on eligibility and safe use of cannabis products.

• Support across Virginia in Richmond, Fairfax, Norfolk, Arlington, Virginia Beach, Roanoke, Chesapeake, and Charlottesville.

Ready to take the next step? Book your appointment today and discover how medical cannabis can improve your quality of life.

FAQs

What makes hemp different from cannabis?

Hemp and cannabis both come from the Cannabis Sativa plant, but they are legally and chemically distinct. Hemp is defined as cannabis that contains less than 0.3% THC, the psychoactive compound that produces a high. Cannabis, on the other hand, often contains much higher levels of THC and is typically grown for medical or recreational use.

Does hemp get you as high as cannabis?

No, hemp does not get you high the way cannabis does. Because hemp contains only trace amounts of THC, it lacks the psychoactive effects associated with marijuana. Cannabis, with higher THC levels, can produce intoxication and euphoria depending on the strain and dosage.

Is hemp better for you than cannabis?

Hemp and cannabis each have unique benefits, so one is not universally “better” than the other. Hemp oil is rich in nutrients like omega-3 and omega-6 fatty acids and is often used for skincare, heart health, and general wellness. Cannabis oil, by contrast, is better suited for patients who need stronger therapeutic effects for conditions such as chronic pain, nausea, or PTSD.

Is hemp another name for cannabis?

Hemp is not simply another name for cannabis—it’s a legal classification of the plant. All hemp is cannabis, but not all cannabis is hemp. The defining factor is THC content: hemp contains less than 0.3% THC, while cannabis grown for medical or recreational purposes often contains much more.

Does hemp oil get you stoned?

No, hemp oil does not get you stoned. Since it is made from hemp seeds and contains only trace amounts of THC, it has no intoxicating effects. People typically use hemp oil for its nutritional value or topical benefits, not for psychoactive purposes.