Cannabis's Tricky Relationship With Mental Health

The relationship between cannabis and mental health is an intricate mosaic. It has been praised as a panacea by some, feared as a Pandora's box by others, and deemed as perplexing by most. As the green wave of marijuana legalization rolls across the globe, a closer look at this controversial relationship is necessary to dispel myths, share realities, and steer users towards responsible consumption.

Can Cannabis Affect Mental Health?

From relaxing the mind to inciting paranoia, cannabis can evoke a spectrum of effects on mental health, largely due to its primary constituents: delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD).

THC, the psychoactive compound, elicits the "high" linked with cannabis use. While it can induce euphoria and a sense of relaxation in some, in others it can lead to anxiety, paranoia, and hallucinations. Several factors, such as dosage, individual tolerance, and the setting of use, contribute to these divergent experiences.

CBD, on the other hand, does not have psychoactive properties, but instead is known for its calming and anti-anxiety effects. The ratio of these two constituents in different strains of cannabis can significantly influence the user's experience.

Moreover, there's growing evidence suggesting that early or heavy cannabis use can increase the risk of developing mental health disorders like depression, anxiety, and psychosis, particularly in individuals with a predisposition to these conditions. The link to schizophrenia is especially concerning, with several studies indicating that regular cannabis use can double the risk of experiencing psychotic symptoms.

Cannabis Use Disorder

Cannabis Use Disorder (CUD) is a diagnosis given to individuals who chronically use cannabis to the detriment of their health, personal life, and daily responsibilities. As per the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), criteria for CUD include increased tolerance, withdrawal symptoms, unsuccessful attempts to quit, and excessive time spent acquiring and using the drug.

Though cannabis is often perceived as non-addictive, research suggests otherwise. While it may not carry the same dependence risk as substances like nicotine or alcohol, approximately 9% of those who experiment with cannabis develop dependence. This figure rises to about 17% for those who start using in their teens, underlining the vulnerability of the developing brain.

CUD can exacerbate existing mental health issues or even trigger new ones. Its relationship with mental health is often bidirectional: pre-existing mental health disorders may lead to increased cannabis use as a form of self-medication, while chronic use can worsen symptoms of these disorders or instigate new ones.

What To Be Aware Of

The association between cannabis and mental health is complex and influenced by several factors, which users should be aware of:

Dosage and THC/CBD ratio: High doses of THC, particularly in the absence of balancing CBD, can result in increased anxiety, paranoia, or even temporary psychosis. Starting with low doses and opting for strains with a balanced THC/CBD ratio can minimize these risks.

Age of first use: Cannabis use during adolescence, when the brain is still developing, increases the risk of both CUD and later mental health disorders. Delaying the initiation of cannabis use until adulthood can significantly mitigate these risks.

Pre-existing mental health conditions: Those with existing mental health conditions are more susceptible to the potential negative effects of cannabis. They may experience symptom exacerbation and are at a higher risk of developing CUD.

The Role of Medical Marijuana in Mental Health Management

Medical marijuana has been hailed as a boon in several jurisdictions where its use has been sanctioned for health-related needs. It has proven beneficial in relieving symptoms linked to chronic pain, multiple sclerosis, and chemotherapy-induced nausea and vomiting. However, the dialogue becomes murkier and more contentious when medical marijuana's efficacy in managing mental health is brought to the table.

A number of individuals have experienced a significant easing of their symptoms post incorporating cannabis, particularly CBD, into their treatment regime. Conditions like anxiety disorders, post-traumatic stress disorder (PTSD), and insomnia have seen promising improvement. Yet, it is crucial to remember that these positive strides do not come without their share of caveats, especially for those with a predisposition to mental health disorders. As we continue to navigate the labyrinth of medical marijuana's therapeutic potential and risks, we find ourselves amidst an extensive and ongoing study over extended periods.

Medical marijuana, while a valuable tool in the therapeutic toolbox, should not be viewed as a standalone solution. It is a single cog in a larger, multifaceted treatment machine that often also includes elements such as psychotherapy, nutritional amendments, and other pharmaceutical interventions. Embarking on a medical marijuana treatment journey to manage mental health conditions should not be a decision in isolation. It is paramount to consult and discuss this choice with healthcare professionals, ensuring that it is a step taken in the right direction toward comprehensive wellness.

How To Use Cannabis Responsibly

There are a number of ways to reduce the hazards associated with cannabis usage and make it more suitable for medical or recreational purposes:

1. Be Familiar with What you Take

The ratio of THC to CBD is a major factor in determining the effects of cannabis. Extreme psychoactive effects, such as anxiety or paranoia, may be triggered by strains with high THC content. These dangers could be reduced by selecting strains with a lower THC to CBD ratio. How it's consumed also makes a difference, whether through smoking, vaping, or eating.

2: Take it Easy at First

For newcomers and those picking up where they left off after an extended absence, adopting the mantra of "start low, go slow" is highly recommended. As your body becomes accustomed to the medication, the dosage can be increased gradually.

3. Pay Attention to Your Surroundings

One's cannabis experience is highly susceptible to one's surroundings. When trying out new strains or greater doses, it's important to do so in a controlled setting, preferably with someone you trust.

4. Hear What Your Body Is Saying

The effects of cannabis on the human body vary greatly. It's crucial to learn and pay attention to how cannabis affects your body individually. Feelings of unease or panic may indicate that you need to reduce your dosage, switch strains, or perhaps forego cannabis use altogether.

5. Recognize the Risks

Risks can only be avoided if you know about them. People having a history of psychosis or other severe mental health illnesses, either in themselves or their families, should use caution while considering cannabis.

6. Consult an Expert

Seek expert guidance before deciding to use cannabis for medical purposes. Doctors and other medical professionals can advise patients on the best course of action, including how often to take a prescription and whether or not it will combine with other drugs.

The complex interplay between cannabis and psychological health highlights the importance of taking a thoughtful, measured, and well-informed approach to using cannabis. We need to keep advocating for appropriate use and learning more about this versatile plant, even as studies and public acceptance grow.

Headshot of Steven Fiore, MD

This article has been reviewed by Steven Fiore, MD.

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