Medical Marijuana for Bulimia

Bulimia

Bulimia nervosa is a severe and life-threatening eating disorder marked by a cycle of binge eating followed by compensatory behaviors, such as self-induced vomiting, excessive use of laxatives or diuretics, fasting, or excessive exercise. Individuals with bulimia have a fear of weight gain and a distorted body image, often evaluating themselves harshly on their weight and shape. The disorder can lead to severe medical complications, impacting both the physical and mental health of the individual.

The Diagnostic and Statistical Manual of Mental Disorders (DSM-5) categorizes bulimia as an eating disorder alongside anorexia nervosa and binge-eating disorder. The disorder affects a substantial portion of the population, primarily women in their teens and early 20s, although it can occur in men and at any age.

Medical Marijuana: An Overview

Marijuana has been used for medical purposes for thousands of years. It was only in the last century that the plant became stigmatized and illegal in many parts of the world. However, in recent decades, the tide has turned, with numerous countries and states in the U.S. legalizing marijuana for medical and/or recreational use.

Medical marijuana refers to using the whole, unprocessed marijuana plant or its extracts to treat symptoms of illness. The U.S. Food and Drug Administration (FDA) has not recognized or approved the marijuana plant as a medicine. However, the agency has approved two medications that contain cannabinoid chemicals in pill form, and more are being researched.

The primary chemicals of interest in marijuana for medical use are Delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). THC produces the "high" people feel when they smoke marijuana or eat foods containing it, while CBD is not psychoactive and is being researched for a variety of medical applications

Cannabis and the Endocannabinoid System

The endocannabinoid system (ECS) is a complex cell-signaling system identified in the early 1990s by researchers exploring THC. While much is still unknown about the ECS, experts do know that it regulates a range of functions and processes, including sleep, mood, appetite, memory, reproduction, and fertility.

Endocannabinoids are molecules made by your body that are similar to cannabinoids. They're part of a complex system that includes endocannabinoids, receptors in the nervous system and around your body that endocannabinoids and cannabinoids bind to, and enzymes that help break down endocannabinoids and cannabinoids.

Cannabinoids like THC and CBD interact with this system, binding to or influencing these receptors, which can affect how you feel, think, and react. This interaction forms the basis for the potential medical uses of cannabis.

Marijuana's Potential Impact on Mental Health

Research has shown that marijuana can have significant effects on mental health, both positive and negative. On one hand, some studies suggest marijuana may help conditions like depression and post-traumatic stress disorder (PTSD). On the other hand, some evidence links marijuana use to increased risk for mental health disorders, like psychosis and substance use disorder.

These contradictory findings suggest that marijuana's impact on mental health may depend on factors like how much and how often it's used, the age at which it's first used, the user's mental health status, and their genetic vulnerability to mental health problems. Understanding the potential mental health effects of marijuana is particularly crucial when considering its use for bulimia, given the high rate of comorbidity between bulimia and other mental health disorders.

Standard Form of Treatment

The primary treatment for bulimia typically involves a combination of psychotherapy, nutritional counseling, and medication. Cognitive-behavioral therapy (CBT) has proven effective in addressing distorted thoughts and behaviors around eating, body shape, and weight. It helps individuals learn healthy ways of coping with stress and other triggers that may lead to binging and purging.

Nutritional counseling plays a critical role in treatment, guiding individuals toward healthier eating patterns and promoting a better understanding of nutritional needs and the harms of bingeing and purging.

Medication, particularly certain types of antidepressants such as selective serotonin reuptake inhibitors (SSRIs), may also be used in conjunction with psychotherapy. SSRIs have been shown to reduce the frequency of binging and purging and alleviate associated depressive and anxious symptoms.

Can Medical Marijuana Help?

Medical marijuana, known for its potential therapeutic properties, has been used in the treatment of various medical conditions, including chronic pain, epilepsy, and multiple sclerosis. As of late, there has been a surge of interest in the potential role of medical marijuana in treating eating disorders, particularly bulimia nervosa.

The human body naturally produces compounds known as endocannabinoids, which are part of a larger endocannabinoid system (ECS) that plays a role in numerous bodily functions, including appetite regulation, stress response, and reward processing. Intriguingly, the active compounds in cannabis, known as cannabinoids, can interact with this system, thereby influencing these functions. This is why marijuana can increase appetite - a phenomenon often called the "munchies."

Given the role of the ECS in appetite and stress response - two key factors in bulimia - it's understandable why researchers are interested in the potential therapeutic application of medical marijuana for this disorder.

What Does The Research Say

While there is still much to be learned about the potential of medical marijuana in treating bulimia, early research and anecdotal reports suggest it may offer some benefits.

A study published in the International Journal of Eating Disorders examined the effects of dronabinol, a synthetic form of THC (the main psychoactive compound in cannabis), on individuals with bulimia and anorexia. The study found that dronabinol reduced self-reported bulimic behaviors, decreased anxiety, and increased body mass index (BMI).

These findings are promising, but they are based on a small sample size, and more robust research is needed to confirm and expand upon these results. It should also be noted that medical marijuana, like all medications, can have side effects. Common side effects of medical marijuana include dizziness, dry mouth, and changes in mood or cognitive function.

The impact of marijuana on mental health is also a topic of ongoing research and debate. Some studies suggest that heavy marijuana use may exacerbate symptoms of mental health conditions, which could be particularly concerning for individuals with bulimia, who often have co-occurring mental health issues like depression or anxiety.

The Bottom Line

Medical marijuana represents a potentially promising but complex and not yet fully understood approach to treating bulimia nervosa. It's clear that more rigorous, large-scale studies are needed to fully elucidate the benefits and risks of this treatment option.

Until then, individuals with bulimia should continue seeking established treatment forms, such as psychotherapy and medication. As our understanding of medical marijuana continues to evolve, it may become a viable adjunct or alternative treatment for some individuals.

Always remember, medical decisions should be made in consultation with a healthcare provider, considering each individual's unique medical history and current health status. It's crucial to consider the potential benefits and risks, including the impact on mental health and the possibility of side effects or drug interactions. If you or a loved one is struggling with bulimia nervosa, reach out to a healthcare provider to discuss the best treatment options.

Headshot of Steven Fiore, MD

This article has been reviewed by Steven Fiore, MD.

Previous
Previous

Cannabis's Tricky Relationship With Mental Health

Next
Next

Medical Marijuana Certification: A Comprehensive Guide to Key Considerations