Why Do Some People Faint When They Use Cannabis?

Introduction

Cannabis is widely used for both medicinal and recreational purposes, celebrated for its relaxing and therapeutic effects. However, not everyone responds to cannabis in the same way. While many people experience mild side effects, such as dry mouth or dizziness, a surprising few may actually faint, or experience “cannabis-induced syncope.” This reaction is often unexpected and can be distressing, especially for new users.

Understanding why fainting occurs in some individuals after cannabis use requires an exploration of how cannabinoids interact with the cardiovascular and nervous systems, as well as the physiological responses of certain individuals. 

This article dives into the science behind cannabis-induced fainting, including the physiological mechanisms at play, the types of cannabis that may increase the risk, and individual factors that make some people more susceptible.

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What is Fainting (Syncope)?

Fainting, or syncope, is a temporary loss of consciousness caused by a sudden drop in blood pressure, resulting in reduced blood flow to the brain. It can be triggered by a variety of factors, from dehydration and sudden changes in position to intense stress or anxiety. When fainting occurs, it is often the body's way of correcting a momentary imbalance or deficiency in blood supply to the brain.

Cannabis use can cause some people to faint by triggering physiological responses that lower blood pressure and slow the heart rate, leading to a temporary loss of consciousness. Cannabis-induced syncope can be both sudden and unexpected, leaving the person disoriented and concerned.

How Cannabis Affects the Body

Cannabis contains a variety of compounds called cannabinoids, the most well-known of which are tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is the psychoactive compound responsible for the “high” associated with cannabis use, while CBD is generally known for its non-psychoactive, therapeutic effects. These cannabinoids interact with the body’s endocannabinoid system (ECS), which plays a key role in regulating mood, appetite, pain perception, and cardiovascular function.

The ECS influences the cardiovascular system by affecting blood pressure, heart rate, and blood vessel dilation. When cannabis is consumed, cannabinoids bind to receptors in the ECS, which can cause vasodilation (widening of blood vessels) and a reduction in blood pressure. For some people, this can lead to a phenomenon known as “orthostatic hypotension,” where blood pressure drops significantly upon standing up, potentially resulting in fainting.

The Role of Orthostatic Hypotension

Orthostatic hypotension is a condition where blood pressure drops quickly when a person stands up, causing dizziness, lightheadedness, or even fainting. This happens because gravity causes blood to pool in the legs when we stand, and if blood pressure isn’t adjusted quickly enough to maintain blood flow to the brain, a person can lose consciousness.

Cannabis, particularly THC, can cause a sudden drop in blood pressure, increasing the risk of orthostatic hypotension. This effect may be stronger in certain individuals, especially those new to cannabis use, as they may not be accustomed to the body’s reaction to THC and other cannabinoids. The result can be fainting or intense dizziness, particularly if a person stands up too quickly after consuming cannabis.

THC and Heart Rate: A Confusing Combination

THC has a complex effect on the cardiovascular system: while it can cause blood pressure to drop, it may also increase the heart rate, a condition known as tachycardia. The paradoxical combination of high heart rate and low blood pressure can be confusing for the body. In some cases, the heart's increased effort may be inadequate to maintain sufficient blood flow to the brain when blood pressure is low, potentially leading to fainting.

People who are particularly sensitive to THC may experience these cardiovascular effects more intensely, and the likelihood of fainting may increase when they consume a high dose of THC, especially in edibles or concentrated forms. Additionally, cannabis-induced anxiety or paranoia, which can further increase heart rate, might compound these effects, increasing the likelihood of fainting.

Related: Is Smoking Weed Bad for Your Heart?

Dehydration and Other Contributing Factors

Cannabis has a tendency to cause dry mouth, and by extension, dehydration, if fluids aren’t consumed regularly while using it. Dehydration can exacerbate the body’s inability to regulate blood pressure effectively, making fainting more likely. In some cases, people may use cannabis in social settings where they consume alcohol, which further dehydrates the body and increases the likelihood of fainting or dizziness.

Another contributing factor can be low blood sugar. Cannabis can sometimes lower blood sugar levels, leading to symptoms of hypoglycemia, such as dizziness, sweating, and weakness. These symptoms, when combined with a drop in blood pressure, can lead to fainting, particularly in individuals who may already have low blood sugar levels or who have gone a long time without eating.

Who Is Most at Risk?

Certain groups are more likely to experience fainting episodes after using cannabis. People who are new to cannabis are often more sensitive to its effects, as their bodies have not yet adjusted to the influence of cannabinoids on their cardiovascular and nervous systems. Additionally, people with pre-existing cardiovascular conditions, such as low blood pressure, arrhythmias, or a history of fainting, may be at greater risk.

Anxiety-prone individuals may also experience higher rates of cannabis-induced fainting, as cannabis can occasionally induce panic or anxiety in susceptible users. This heightened stress response can exacerbate the physiological effects of cannabis, leading to more pronounced drops in blood pressure or heart rate irregularities. Additionally, older adults may be more susceptible to cannabis-induced fainting, as the body's cardiovascular and nervous systems become less adaptable with age.

Ways to Prevent Cannabis-Induced Fainting

For those concerned about fainting from cannabis, there are several steps that can reduce the risk.

  1. Start with Low THC Strains: Choosing cannabis strains that are low in THC and higher in CBD may help reduce the risk of cardiovascular side effects, as CBD is less likely to cause a dramatic drop in blood pressure or an increase in heart rate.

  2. Stay Hydrated: Drinking plenty of water before and after cannabis use can prevent dehydration, which can contribute to fainting.

  3. Take It Slow: Consuming cannabis slowly, especially if using an edible, can allow the body time to adjust to its effects, reducing the likelihood of sudden dizziness or lightheadedness.

  4. Avoid Alcohol and Caffeine: Alcohol can exacerbate dehydration, while caffeine can increase heart rate. Avoiding both substances when using cannabis can help prevent fainting.

  5. Change Positions Slowly: Avoid standing up quickly after using cannabis, as this sudden movement can trigger orthostatic hypotension. Taking a few moments to sit before standing can reduce the risk.

  6. Use with Caution if You Have a Heart Condition: People with pre-existing cardiovascular conditions should consult with a healthcare professional before using cannabis, as they may be at increased risk for fainting.

Final Thoughts

While fainting is a rare side effect of cannabis use, it can be an alarming experience for those who encounter it. The primary causes—sudden drops in blood pressure, heart rate fluctuations, dehydration, and individual sensitivity to THC—highlight the complex ways in which cannabis interacts with the body’s cardiovascular and nervous systems.

By understanding the factors that lead to cannabis-induced fainting and taking preventive measures, users can enjoy cannabis more safely. If someone has a fainting episode after using cannabis, it’s essential to stay calm, remain seated, and breathe slowly. Anyone with ongoing concerns or underlying health issues should consult a healthcare provider to ensure that cannabis is a safe option for them.

 

FAQs

  • Fainting itself is usually not harmful and lasts only a few seconds to a few minutes. However, falling during a fainting episode can lead to injury. Repeated episodes of fainting may indicate an underlying cardiovascular or health issue, so if someone experiences frequent fainting with or without cannabis, they should consult a healthcare provider.

  • People who are new to cannabis, individuals with low blood pressure, or those using high-THC products are at higher risk of fainting. Other risk factors include dehydration, fasting or low blood sugar, a history of fainting or anxiety, and using alcohol or caffeine alongside cannabis. Older adults may also be more susceptible.

  • Yes, there are ways to reduce the risk of fainting. Start with low-THC strains or microdose to ease into cannabis’s effects. Staying hydrated, eating a balanced meal before using, avoiding alcohol or caffeine, and changing positions slowly after using cannabis can all help reduce fainting risks. Choosing cannabis products with a higher CBD-to-THC ratio may also minimize these side effects.

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This article has been reviewed by Steven Fiore, MD.

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